The detection of MRD has multiple clinical applications:
Prognostic Indicator: The presence of MRD after treatment is often associated with a higher risk of relapse. Conversely, MRD negativity is usually a good prognostic sign. Treatment Adjustment: MRD levels can guide the intensification or de-escalation of therapy. For instance, a patient who is MRD-positive may require additional treatment cycles. Monitoring Relapse: Regular MRD testing can help in early detection of relapse, allowing for timely intervention.
