What are the Common Causes of Hepatotoxicity in Cancer Patients?
Several factors can contribute to hepatotoxicity in cancer patients:
Chemotherapy Drugs: Many chemotherapy agents, such as methotrexate, doxorubicin, and cyclophosphamide, are known to cause liver damage. Targeted Therapy: Drugs like tyrosine kinase inhibitors (TKIs) and monoclonal antibodies can lead to liver toxicity. Immunotherapy: Agents that boost the immune system, such as checkpoint inhibitors, can sometimes cause immune-mediated liver damage. Radiation Therapy: Radiation aimed at liver tumors or nearby areas can inadvertently damage healthy liver tissue. Underlying Liver Conditions: Pre-existing conditions like hepatitis or fatty liver disease can exacerbate the risk of hepatotoxicity.
