What Are the Current Challenges in Epigenomic Research in Cancer?
Despite the promising potential of epigenomic research, several challenges remain:
- Complexity: The intricate interplay between various epigenetic mechanisms makes it difficult to pinpoint specific changes responsible for cancer. - Heterogeneity: Tumor cells can exhibit significant epigenetic heterogeneity, complicating the identification of universal biomarkers. - Technological Limitations: Advanced techniques like single-cell epigenomics are still evolving and are often costly, limiting their widespread use.