What Are the Key Applications of scRNA-seq in Cancer?
1. Identifying Cancer Stem Cells: scRNA-seq helps in identifying and characterizing cancer stem cells, which are often responsible for relapse and metastasis. 2. Mapping Tumor Microenvironment: It provides detailed maps of the immune cells, stromal cells, and other components of the tumor microenvironment. 3. Understanding Drug Resistance: By comparing gene expression profiles before and after treatment, researchers can identify mechanisms of drug resistance. 4. Personalized Medicine: scRNA-seq data can guide the development of personalized treatment plans by identifying unique cellular signatures within a patient’s tumor.
