Several ethical considerations guide the IRB's review of cancer research:
1. Informed Consent: Participants must be fully informed about the study's purpose, procedures, risks, and benefits. Consent must be given voluntarily. 2. Risk-Benefit Analysis: The IRB evaluates whether the potential benefits of the research outweigh the risks to participants. 3. Confidentiality: Measures must be in place to protect participants' personal and medical information. 4. Vulnerable Populations: Extra precautions are taken to protect vulnerable groups, such as children or terminally ill patients. 5. Conflict of Interest: Researchers must disclose any potential conflicts of interest that could affect the study's integrity.