Several tools and databases are commonly used for functional annotation clustering in cancer research: - DAVID (Database for Annotation, Visualization, and Integrated Discovery): A comprehensive tool for functional annotation and clustering of large gene lists. - STRING (Search Tool for the Retrieval of Interacting Genes/Proteins): A database of known and predicted protein-protein interactions. - Enrichr: An interactive and user-friendly tool for performing gene set enrichment analysis and functional annotation. - Gene Ontology (GO): A widely used database for annotating genes and proteins with biological processes, cellular components, and molecular functions. - KEGG (Kyoto Encyclopedia of Genes and Genomes): A database for understanding high-level functions and utilities of the biological system.