What Are the Key Types of Genetic Alterations in Cancer?
There are several types of genetic alterations commonly observed in cancer:
1. Mutations: Changes in the DNA sequence that can be benign or pathogenic. 2. Copy Number Variations: Changes in the number of copies of a particular gene. 3. Structural Variations: Large-scale alterations in DNA structure, such as translocations and inversions. 4. Epigenetic Changes: Modifications in gene expression without altering the DNA sequence.
