Despite their benefits, targeted therapies also have limitations:
1. Resistance: Cancer cells can develop resistance to targeted therapies, rendering them ineffective over time. 2. Limited applicability: Not all cancers have identifiable targets or mutations that can be treated with targeted therapies. 3. Cost: These treatments can be expensive and may not be covered by all insurance plans. 4. Side effects: While generally fewer, targeted therapies can still cause side effects such as fatigue, skin rashes, and diarrhea.