The most commonly used radionuclides in PRRT are Yttrium-90 (90Y) and Lutetium-177 (177Lu). Each has unique properties that make them suitable for different clinical scenarios:
- Yttrium-90 (90Y): Emits high-energy beta particles and is typically used for treating larger tumors because of its longer tissue penetration. - Lutetium-177 (177Lu): Emits both beta and gamma particles and has a shorter tissue penetration range, making it more suitable for treating smaller tumors and allowing for imaging during therapy.
