What Are the Mechanisms Behind Serotonin's Role in Cancer?
Serotonin exerts its effects through binding to various serotonin receptors, which are G protein-coupled receptors present on the surface of cells. Different serotonin receptors can trigger distinct signaling pathways, leading to varied biological effects. For example, the activation of the 5-HT2A receptor has been linked to cell proliferation, whereas the 5-HT1B receptor might be involved in inducing apoptosis or programmed cell death.
