What Are the Mechanisms of Styrene-Induced Carcinogenesis?
The exact mechanisms by which styrene may cause cancer are not fully understood. However, it is believed that styrene metabolism plays a significant role. Styrene is metabolized in the body to form styrene oxide, a reactive intermediate that can bind to DNA and proteins, potentially causing mutations and cellular damage. Additionally, styrene and its metabolites can induce oxidative stress and inflammation, which are known contributors to cancer development.