Like all medications, crizotinib has a range of potential side effects. Common side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, and constipation. Patients may also experience visual disturbances, including blurred vision and flashes of light. Other side effects include edema, fatigue, and elevated liver enzymes. Serious but less common side effects include pneumonitis and QT interval prolongation, which require immediate medical attention.