Symptoms of metastatic cancer can vary widely depending on the location of the metastases. For example: - Bone Metastasis: Can cause pain, fractures, and increased calcium levels. - Liver Metastasis: May lead to jaundice, abdominal pain, and weight loss. - Lung Metastasis: Can result in shortness of breath, chest pain, and a persistent cough. - Brain Metastasis: Might cause headaches, seizures, and neurological deficits.