What are the therapeutic implications of MHC in cancer?
Understanding the role of MHC in cancer has led to several therapeutic strategies: - Cancer vaccines can be designed to enhance the presentation of tumor antigens via MHC molecules. - Immunotherapy techniques, such as checkpoint inhibitors, aim to restore the immune system’s ability to recognize and attack cancer cells. - CAR-T cell therapy involves engineering T cells to better recognize cancer cells irrespective of MHC presentation.