major histocompatibility complex

What are the therapeutic implications of MHC in cancer?

Understanding the role of MHC in cancer has led to several therapeutic strategies:
- Cancer vaccines can be designed to enhance the presentation of tumor antigens via MHC molecules.
- Immunotherapy techniques, such as checkpoint inhibitors, aim to restore the immune system’s ability to recognize and attack cancer cells.
- CAR-T cell therapy involves engineering T cells to better recognize cancer cells irrespective of MHC presentation.

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