genome integrity

What Are the Therapeutic Implications of Targeting Genome Integrity?

Targeting genome integrity has therapeutic implications in cancer treatment. Inhibitors of PARP (poly ADP-ribose polymerase) have shown efficacy in treating cancers with BRCA mutations by exploiting the concept of synthetic lethality. Additionally, strategies to enhance DNA repair capacity or protect genome integrity could be used to prevent cancer development in high-risk individuals.

Frequently asked queries:

What is Genome Integrity?
How Does Genome Instability Lead to Cancer?
What Are the Mechanisms That Maintain Genome Integrity?
How Do Mutations in DNA Repair Genes Contribute to Cancer?
What Role Do Environmental Factors Play in Genome Instability?
Can Genome Editing Technologies Help in Cancer Treatment?
What Are the Therapeutic Implications of Targeting Genome Integrity?
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