What are the Therapeutic Implications of Targeting PAX3?
Targeting PAX3 presents a promising strategy for cancer therapy. Potential approaches include: 1. Gene Silencing: Techniques like RNA interference (RNAi) can be used to silence PAX3 expression, thereby inhibiting cancer cell growth. 2. Small Molecule Inhibitors: Developing small molecules that specifically inhibit the PAX3-FOXO1 fusion protein or its downstream targets. 3. Immunotherapy: Designing immunotherapeutic approaches to target PAX3-expressing cells.
