Treatment of cGVHD aims to suppress the donor immune cells while minimizing side effects. Options include:
Corticosteroids to reduce inflammation Immunosuppressive agents such as cyclosporine and tacrolimus Biologic therapies like rituximab and ibrutinib Supportive care measures including physical therapy and nutritional support
In refractory cases, extracorporeal photopheresis (ECP) and other advanced therapies may be considered.
