Several types of adaptive designs are used in cancer trials, including:
Group Sequential Designs: Allow for early stopping based on interim analysis results, either for efficacy or futility. Bayesian Adaptive Designs: Use Bayesian statistics to update the probability of treatment success as new data becomes available. Adaptive Dose-Finding Designs: Help identify the optimal dose of a new treatment by adjusting doses based on patient responses. Seamless Phase II/III Designs: Combine phases of clinical trials to accelerate the process and reduce resource use.
