What are the Types of Genomic Technologies Used in Cancer Research?
Multiple genomic technologies are instrumental in cancer research, including:
Whole Genome Sequencing (WGS): This method sequences the entire genome of cancer cells to identify all genetic alterations. Whole Exome Sequencing (WES): Focuses on sequencing the protein-coding regions of the genome, which are most likely to contain disease-causing mutations. RNA Sequencing (RNA-Seq): Analyzes the RNA in cancer cells to understand gene expression patterns. Copy Number Variation (CNV) Analysis: Detects changes in the number of copies of particular genes, which can drive cancer development. Methylation Profiling: Studies DNA methylation patterns, which can regulate gene expression and are often altered in cancer.