Several cancer treatments are known to be associated with cardiotoxic effects. These include:
1. Anthracyclines: Drugs like doxorubicin and daunorubicin are highly effective but are notorious for causing cardiotoxicity, especially at higher cumulative doses. 2. HER2 Inhibitors: Agents such as trastuzumab, used in breast cancer treatment, can lead to heart failure, particularly when used in combination with anthracyclines. 3. Tyrosine Kinase Inhibitors: Drugs like imatinib and sunitinib, used in various cancers, have been linked to hypertension and heart failure. 4. Radiation Therapy: Especially when targeting areas near the heart, radiation can cause myocardial fibrosis, pericarditis, and accelerated atherosclerosis.
