The exact cause of glioblastoma is not well understood. However, several risk factors have been identified, including:
- Genetic predisposition: Certain genetic syndromes, such as Li-Fraumeni syndrome and Turcot syndrome, are associated with a higher risk of developing glioblastoma. - Exposure to ionizing radiation: Individuals who have undergone radiation therapy for other cancers have an increased risk of developing glioblastoma. - Age: The risk of glioblastoma increases with age.