What Challenges Exist in Epigenetic Cancer Research?
Despite significant advancements, several challenges remain:
1. Complexity and Variability: The epigenome is highly dynamic and context-dependent, making it challenging to pinpoint specific changes associated with cancer. 2. Drug Resistance: Cancer cells can develop resistance to epigenetic therapies, necessitating combination treatments and new therapeutic strategies. 3. Off-Target Effects: Epigenetic drugs can affect multiple genes, leading to unintended consequences and side effects.
