What Factors Contribute to Biological Variability in Cancer?
Several factors contribute to the biological variability seen in cancer:
Genetic Mutations: Different types of genetic mutations can drive cancer development and influence its behavior. Epigenetic Changes: Modifications that do not alter the DNA sequence but affect gene expression can also play a significant role. Microenvironment: The tumor microenvironment, including surrounding cells and extracellular matrix, can impact cancer growth and response to treatment. Immune System: Variability in the immune response to cancer cells can affect disease progression and treatment outcomes. Lifestyle Factors: Diet, smoking, alcohol consumption, and physical activity can influence cancer risk and progression.
