Several factors can influence cumulative risk, including:
Genetic factors: Family history and inherited genetic mutations (e.g., BRCA1 and BRCA2) can significantly elevate risk. Lifestyle factors: Smoking, diet, alcohol consumption, and physical activity levels play crucial roles. Environmental exposures: Exposure to carcinogens such as asbestos, radiation, and certain chemicals can increase risk. Age: The risk of developing cancer generally increases with age. Pre-existing medical conditions: Certain chronic conditions like obesity or diabetes may elevate risk.