Several factors can influence dose adjustments, including:
Tumor Characteristics: Type, size, and location of the tumor can affect how drugs are distributed and absorbed. Patient Factors: Age, weight, and genetic predisposition to certain drug reactions. Organ Function: Liver and kidney function are critical for drug metabolism and excretion. Impaired organ function may require dose reductions. Previous Treatment Responses: How a patient has responded to previous treatments can guide future dose adjustments.