What Factors Influence the Invasive Potential of Cancer?
The invasive potential of cancer is influenced by a combination of genetic, molecular, and environmental factors. Genetic mutations can activate oncogenes and inactivate tumor suppressor genes, leading to uncontrolled cell proliferation and invasive behavior. Moreover, the tumor microenvironment, including immune cells, fibroblasts, and the ECM, can either support or hinder cancer invasion, depending on the interactions and signals present.