What is Hypoxanthine Guanine Phosphoribosyltransferase (HPRT)?
Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) is an enzyme that plays a critical role in the purine salvage pathway, which is essential for nucleotide metabolism. The enzyme is responsible for converting hypoxanthine and guanine into their respective nucleotides, IMP and GMP. This process is crucial for maintaining the balance of purine nucleotides in cells.