Lymphoma refers to a group of blood cancers that develop in the lymphatic system. Adult T-cell leukemia/lymphoma (ATLL) is a rare and aggressive type of lymphoma caused by the human T-cell lymphotropic virus type 1 (HTLV-1). This virus infects T-cells, a type of white blood cell important for the immune system. ATLL is most common in regions with a high prevalence of HTLV-1, such as Japan, the Caribbean, and parts of Africa.