Mandatory Access Control (MAC) is a type of access control in which the operating system constrains the ability of a subject (e.g., a user or process) to access or perform operations on an object (e.g., a file or data). The security policy is centrally controlled by an administrator and is not modifiable by users. In the context of cancer research and healthcare, MAC ensures that sensitive patient data and critical research information are protected from unauthorized access and breaches.