human leukocyte antigen (hla)

What is the impact of HLA typing in cancer immunotherapy?


HLA typing is the process of determining the specific HLA alleles an individual possesses. This information is critical for the success of some cancer immunotherapies, such as CAR-T cell therapy and TCR-engineered T cell therapy. Knowing a patient's HLA type can help in the design of personalized treatments that are more likely to be effective. Additionally, HLA typing is essential for matching donors and recipients in bone marrow and organ transplants, which can be part of the treatment plan for some cancers.

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