What Is the Protective Effect Against Solid Tumors?
Interestingly, individuals with Down syndrome have a lower incidence of solid tumors, such as breast, colon, and prostate cancers. Researchers hypothesize that genes located on chromosome 21, including those involved in tumor suppression, may offer protective benefits. For instance, the gene DSCR1 (Down syndrome critical region 1) has been implicated in inhibiting angiogenesis, the process by which tumors develop their own blood supply.
