What is the Role of CXCR4 in Tumor Microenvironment?
The tumor microenvironment is a complex network of cells and signaling molecules that surround and interact with tumor cells. CXCR4 plays a critical role in this environment by influencing angiogenesis, immune evasion, and the recruitment of stromal cells that support tumor growth. By attracting immune suppressor cells and promoting blood vessel formation, CXCR4 helps tumors to grow and evade immune detection.