glutathione s transferase

What is the Role of GST Polymorphisms in Cancer Risk?

Genetic polymorphisms in GST genes can influence individual susceptibility to cancer. Variations in genes encoding GST enzymes, such as GSTP1, GSTM1, and GSTT1, may affect enzyme activity and detoxification capacity. Certain polymorphisms are associated with increased cancer risk or altered response to chemotherapy.

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