What is the Role of Immune Checkpoints in Immune Evasion?
Immune checkpoints are regulatory pathways in the immune system that help maintain self-tolerance and modulate the duration and amplitude of immune responses. Cancer cells can exploit these checkpoints to avoid immune attack. For example, the interaction between PD-1 on T cells and PD-L1 on tumor cells can inhibit T cell function, allowing the tumor to evade the immune response.
