What is the Role of Necrosis in Cancer Progression?
Necrosis in tumors can have both tumor-promoting and tumor-suppressing effects. On one hand, the release of cell debris and inflammatory molecules from necrotic cells can stimulate the immune response and inhibit tumor growth. On the other hand, chronic inflammation and the release of growth factors from necrotic cells can create a microenvironment that supports tumor progression and metastasis.
