What is the Role of Oncogenes and Tumor Suppressor Genes?
Oncogenes are genes that, when mutated, can promote cancer cell growth. Examples include HER2 in breast cancer and KRAS in colorectal cancer. Tumor suppressor genes, such as TP53 and BRCA1, normally prevent uncontrolled cell division. Mutations in these genes can lead to a loss of function, contributing to cancer progression.