What Is the Role of Protein Phosphorylation in Cancer?
Protein phosphorylation is a process in which a phosphate group is added to a protein, altering its function and activity. This is a critical mechanism in cell signaling pathways that regulate cell growth and division. Aberrant phosphorylation due to mutations in kinases or phosphatases can lead to uncontrolled cell proliferation and cancer. Drugs that target these aberrant phosphorylation events are being developed as cancer therapies.
