What Is the Significance of Lipid Metabolism in Cancer?
Lipid metabolism is another area where cancer cells show significant alterations. Increased lipogenesis is commonly observed in cancer cells, driven by the overexpression of enzymes like fatty acid synthase (FASN). Enhanced lipid synthesis contributes to the formation of cellular membranes, energy storage, and the production of signaling molecules. These lipids also play a role in modifying the tumor microenvironment, promoting cancer cell survival and proliferation.