What Mechanisms are Involved in Fork Stabilization?
Several cellular mechanisms are involved in fork stabilization, including the action of proteins like ATR (Ataxia Telangiectasia and Rad3-related protein), Chk1 (Checkpoint kinase 1), and BRCA2 (Breast Cancer type 2 susceptibility protein). These proteins help detect and repair DNA damage, stabilize the replication fork, and facilitate the restart of stalled forks.
