Several methods are employed in the discovery of therapeutic targets:
Genomic Sequencing: Identifies genetic mutations and alterations in cancer cells. Proteomics: Studies the protein expression and modifications in cancer cells. RNA Sequencing: Analyzes gene expression profiles in cancer cells. CRISPR-Cas9 Screening: Utilizes gene editing to identify essential genes for cancer cell survival. Bioinformatics: Integrates data from various sources to predict potential targets.