Several statistical methods can be used to handle left censoring in cancer research:
Imputation Techniques: These involve estimating the missing onset times based on available data and incorporating these estimates into the analysis. Survival Analysis Models: Specialized models like the Turnbull Estimator can be used to incorporate left-censored data effectively. Using Interval Censoring: This approach treats the onset time as an interval rather than a fixed point, allowing for more flexible modeling.