Membrane proteins are critical in the behavior of cancer cells. Key membrane proteins involved in cancer include:
Growth Factor Receptors: These receptors, such as EGFR (Epidermal Growth Factor Receptor) and HER2, can become overactive in cancer cells, leading to uncontrolled cell division. Adhesion Molecules: Proteins like integrins and cadherins are involved in cell adhesion and migration, and their dysregulation can promote metastasis. Transport Proteins: These proteins regulate the transport of ions and small molecules across the cell membrane, and their altered activity can affect the cellâs internal environment and survival.