What Role Do Mitochondria Play in Cancer Metabolism?
Mitochondria are the powerhouses of the cell, responsible for producing the majority of cellular ATP through oxidative phosphorylation. In cancer cells, mitochondrial function is often reprogrammed to balance energy production with the need for biosynthetic intermediates. This reprogramming can involve changes in mitochondrial dynamics, such as fusion and fission, as well as alterations in the expression of mitochondrial enzymes.