What Role Does Photodegradation Play in Photodynamic Therapy (PDT)?
In PDT, a photosensitizing agent is administered to the patient and then activated by a specific wavelength of light. The activated agent produces ROS that target and kill cancer cells. Photodegradation of the photosensitizing agent needs to be carefully controlled to ensure it remains effective until it reaches the tumor site. Excessive photodegradation before activation can reduce the treatment efficacy, whereas controlled degradation post-activation can help minimize side effects.
