What Types of Cancer Are Associated with DNA Repair Deficiency?
Several types of cancer are linked to defects in DNA repair mechanisms. These include:
Breast Cancer - Often associated with mutations in BRCA1 and BRCA2. Ovarian Cancer - Also linked to BRCA1 and BRCA2 mutations. Colorectal Cancer - Frequently related to deficiencies in mismatch repair genes like MLH1 and MSH2. Lynch Syndrome - An inherited condition that increases the risk of colorectal cancer and is associated with mismatch repair deficiencies. Fanconi Anemia - A rare genetic disorder that leads to DNA repair defects and increased cancer risk.
