What Types of Cancer are Targeted by ATR Inhibitors?
ATR inhibitors have shown promise against various types of cancer, including ovarian, colorectal, and lung cancers. They are particularly effective in cancers with deficiencies in other DNA repair mechanisms, such as those with BRCA1 or BRCA2 mutations. These cancers are more reliant on ATR for survival, making them more susceptible to ATR inhibition.