What Types of Cancers are Associated with EGFR Family Alterations?
Alterations in the EGFR family are implicated in several types of cancer. These include:
Non-small cell lung cancer (NSCLC): Often associated with activating mutations in EGFR. Breast cancer: Frequently involves overexpression or amplification of HER2. Colorectal cancer: EGFR overexpression is a common feature. Head and neck squamous cell carcinomas: Often exhibit EGFR overexpression. Bladder cancer: EGFR and HER2 alterations have been reported.
