epigenetic drugs

What Types of Epigenetic Drugs Are Currently Available?

Several classes of epigenetic drugs have been developed, including:
DNA methyltransferase inhibitors (DNMTis): These drugs prevent the addition of methyl groups to DNA, thereby reactivating silenced tumor suppressor genes.
Histone deacetylase inhibitors (HDACis): These compounds inhibit the deacetylation of histones, leading to a more relaxed chromatin structure and increased gene expression.
Bromodomain and extra-terminal domain inhibitors (BETis): These drugs block the interaction between bromodomains and acetylated histones, affecting the expression of oncogenes.

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