genome

What Types of Genetic Mutations Lead to Cancer?

Mutations can be broadly categorized into somatic and germline mutations. Somatic mutations occur in non-reproductive cells and are not inherited, while germline mutations are present in reproductive cells and can be passed on to offspring. Key types of mutations include:
Point mutations: Changes in a single nucleotide base pair.
Insertions and deletions: Addition or loss of small DNA segments.
Copy number variations: Duplications or deletions of large segments of DNA.
Chromosomal rearrangements: Large structural changes like translocations, inversions, or duplications.

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