Which Cancer Treatments Are Most Likely to Cause Renal Impairment?
Certain cancer treatments are more likely to cause renal impairment. These include:
- Chemotherapy Agents: Drugs like cisplatin, methotrexate, and ifosfamide are known for their nephrotoxic effects. - Targeted Therapies: Agents like bevacizumab and sunitinib can lead to hypertension and proteinuria, which may progress to renal dysfunction. - Immunotherapy: Drugs such as checkpoint inhibitors can cause immune-related adverse events, including nephritis. - Radiation Therapy: Particularly when directed at or near the kidneys, radiation can cause damage to renal tissues.
